My Mandy has lived in a bedroom for over 2 years now. During the day, the door is open. The other cats come and go, but she chooses not to come out. At night and if I will be gone long, I must close the door as Tommy will go in and the 2 of them fight. With her being a petite 6 pound gal and him an 11 pound muscle man, he really could hurt her. While I am home, if he ventures in that room she immediately sounds the alarm, and I run in to squirt him. He KNOWS he is supposed to ignore her. She has food, water, litter boxes (2) in there, and a 3 tier perch with a window view. Outside of that room, I have 8 litter boxes, and of course plenty of water bowls and food (out of the dogs' reach). It is her choice to stay in there, IMO. She is free to come out if she wants. Yeah, Tommy is a pain, but he does this with anyone who lets him. Ebony took over a year to swatch him on the nose and that is all it took.

So as someone else said, living in a bedroom is not all bad.