I bought one of these rawhides on a whim for Autumn a few weeks ago and she had the runs for a week! We blamed it on the lamb and rice formula my mom was giving her when she dogsat (same brand I give but a different flavor). Luckily I bought a 3 inch bone and she's a 45 pound dog. Thank you for bringing this to my attention. Never again will she get this brand! I'll be sure to help spread the word.