I have a friend whose sister was a travel nurse for a couple of years. She would move around 3 or 4 times a year. 13-week assignments and if she really liked it she could request a second 13 weeks. She pretty much stayed in warm climates- Hawaii, Florida, Texas. She said the hardest things were not acquiring lots of "stuff" and getting her nursing license verified. The agency she worked for helped with housing. Then she wanted to put down roots so she took an assignment in Michigan, near her family, that ended up becoming a permanent position.