I'd have to say Great Dane. I love the Harlequin! St. Bernards are beautiful too! I really prefer the short-coated bernards vs. the long-coat.

Actually my favorite of the larger breeds is the Bernese Mountain Dog. Landseer newfoundlands are also adorable!

I'm not sure if I could handle the drool either....and I'd definitely have to get a new vehicle, it's bad enough with a 45 lb husky!