When mine were babies, I fixed them a box to sleep in and shut them in the bathroom while I was at work. Now, I put them in the kitchen when I have to go somewhere. I put a plastic thing over the refrigetator cord so they can't chew threw it. They have the run of about a 2 room area because the kitchen used to be two rooms.

I guess I'd say kitten proof one or two rooms for her. I've not been gone for long periods though since I have been disabled for 15 years. Give her tons and tons of toys and things to keep her busy.

My brother does the same thing. He has nine cats now. Just found two new widdle ones. He fixes a place for them in his home office until they are old enough to meet the rest of his gang. Hope this helps some.