My Josh & Sabrina are the same way.
With Sabrina I only have to confine her for an afternoon, or whole day if she's really upset.
Josh has to be confined for 3 days with minimal interaction so he gets lonely enough that he's willing to try and get along with everyone. I feel bad about doing it, but when he gets that upset he has been known to launch at my face, and he's normally a sweet, loving kitty.
At that when I let each one back out I have to supervise for awhile and try to do it when the other cats are sleeping so they don't have contact right away.
I've also taken to leaving ALL the cat carriers out so they smell like home, seems to make the one going smell less strange when they come back if it's just a quick vet visit. All bets are off if the cat going has to stay or pees themselves at all.
I totally understand what you're going through.
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