Yes that is a side effect of the medicine. I've had 3 cats developed hyperthyroid disease, and all of mine died soon after diagnosis (less than a year).

I didn't know it came in a cream now, I was always having the pill form.

At 5.3 pounds, he isn't going to last much longer either way, you do realize that? Last one my vet scolded me for waiting too long to bring her in, she was a bit under that weight but not by much.

I've not read of any way to "reverse" kidney failure. You can treat it, with sub Q fluids, I did that on my RB Amber. and give a low prrotein diet, which puts less stress on the kidneys, thus slowing down the course of the disease. I'd be interested in hearing how the homeopathic vet would address this.

And wouldn't you, for Murphy, as well?