Nope, no changes in personality whatsoever and no constipation either. No problems at all or I would've taken them off it. I have blood work done once a year just to be on the safe side but they've been on it for approximately 6 years now and all is well.

My cats are easy to pill so I just tilt their heads back and pop the pill in but do whatever works for you. I buy the 20 mg. pills and cut them into quarters so that they're so small the cats barely notice when I pop a pill in. Just be sure not to miss a dose; that's key, and if you give it to them at bed time, they'll be calm and most likely will sleep through the night, no night time antics. As I said, it doesn't drug them, just prevents their nasty habits. Boo, my blackie, has a bad gag reflex so I give him a little dab of Cat Lax to coat his stomach a little and to help it go down smoothly and that works just fine. Specs, my Maine Coon, gets dosed morning and night b/c he's a big boy and he's more prone to act up. If you could see him, though, you'd never notice a difference. He's completely alert, active and a general pain in the patootie. LOL