I know that this may sound a bit cruel, but when I had my semi-feral cat Cirrus I had to put an open carrier behind the toilet and chase him into my bathroom while quickly closing the door. I then had to use a broom to chase him into the carrier and then I had to quickly close it. I could never pick this cat up and he would growl and hiss like a wild cat. I did get some sedative pills for him but I could never get him to take them. I had to bring him in a bit early to have a vet tech give them to him. How he managed to do it I have no idea. They also make this in a cream that you could rub into his ear. Maybe this would work out better. Good luck.