A commercial washer and dryer should handle it. I've done king size comforters in them, and they work fine.

If you don't want to take a chance with that, try Febreze Pet Odor Eliminator. Spray it real good and then put it outside on a sunny day and leave it in the sun all day. This works good too. You might want to try this as a first option if you think the washer might tear it up.