I buy things online quite frequently. The town I live in is so small that our walmart (which is our only convenient store) doesn't always have everything I am looking for. I mainly purchase things online from Ebay, Pacsun, ThinkGeek, etc. I have never had a bad experiance so far, and it is much more conveniant than driving an hour to a larger town.

As for things I wouldn't buy online, like Anna, I wouldn't buy a car... Or a house. I am also reluctant to buy electronics unless I am buying straight from the actual company.