I forgot to say that Molly was on the transdermal because the Tapazole by mouth upset her stomach. Also, I buy the pills from our vet, that is cheaper than going to the human pharmacy. The transdermal cream is dispensed for 30 days(at least that is how the pharmacy we used in NJ dispensed it). It is involved and you do have to wear gloves. You rotate the cat's ears. We used the right ear in the morning, and used the left ear in the evening(that was all that was LEFT to do). The tip of the ear is washed to remove all the transdermal med that may be left. In the evening, we washed the right ear off so it would be ready to use in the morning, and the left ear was washed in the morning, so it would be ready for the evening application. I know it sounds like alot, be Barry and I did this for several years....if you have any questions, please ask!!! Sandra