I use DES in two of my females. Sleet takes it once a week. She stopped having accidents after the second dose. She just had a bit of leakage, mostly when asleep.

Pirate had absolutely no bladder control when she got here. Urine just poured out of her! it was awful for her! She takes DES every four days. Within two weeks she had perfect bladder control.

I find it highly amusing that DES has caused me nothing but problems in my personal health(I am a DES daughter, my Mom was prescribed it when she was pregnant). But it has given my two girls back their comfort and dignity. In Pirate's case, it's helped save her life. I'd have probably had to let her go if it hadn't worked.