Awww, Mary...

Just wondering if she acted weird immediately after each dose of Epogen...

It's sweet but painful how she cried to you as if for help. "Mommy knows!"

Would a covered litterbox in the bathroom help at all? (or uncovered if that doesn't gross you out).

I hope Dr Lee has some insight - even over the phone. I know she is taking lots of meds already - just wondering if Omega 3-6 oil mixed in with her food would help? My boys get about 1/2 tsp each if that, mixed up in their wet food.

I am so sorry this is happening...I do hope there is another answer.

HUGS!

ETA - I am at work, but I just HAD to try and look something up. This page is interesting, and I copied this part from it:

Breathing becomes less efficient at delivering oxygen to the blood, because the lungs become less flexible and the muscles involved in breathing weaken. This may contribute to problems such as tiredness on exercise, and altered behavior associated with senility.
http://www.sniksnak.com/cathealth/aging.html

Also, Cognitive Dysfunction Syndrome (CDS):

http://www.fabcats.org/owners/elderly/senility.html

The cat’s response to this stress is to show more obvious signs of CDS (e.g. anorexia, hiding, and/or upset of toileting habits).
The most commonly seen changes include spatial (space) or temporal (time) disorientation, altered interaction with the family, changes in sleep-wake cycles, house-soiling with inappropriate urination/defecation, changes in activity, and/or inappropriate vocalisation (often displayed as loud crying at night)
Mary - in the second link, scroll way down for Max's case story. This article is in small print, but it does list treatment options. Just scan for the parts relating for that; it's a lot to read.

If nothing else, print out both links and fax 'em over to Doc Lee. Also - and I am not making this up - both pages referred to the Omega 3 - 6 stuff.

There IS a drug too, but that's not what poor Puddy needs!

Just trying to picture her with a wee kitty nebulizer for her doses of oxygen! :-)