I'm on it. I had a hysterctomy almost two years ago and I'm still trying to get the HRT type/dosage figured out but I think I'm almost there. Since I was put into surgical menopause and it wasn't a gradual thing I don't know if I'm any help but I can tell you that I went about 6 months with no HRT last summer and I almost went insane from the hot flashes, night sweats and mood swings. I've never suffered depression but I'd say I has some seriously down days.

I've tried several different types of HRT and so far Vivelle Dot has been the best. I like that it's a patch I change every three days and it's easier on my body being absorbed through the skin and not going through my internal organs.

I'm 40 years old so I definetely need it but I can tell you that I will taper off when I reach what would have been a normal menopause age for me. I'm trying to take the lowest dose of estrogen possible because my mother had breast cancer and I don't want to make my risk any greater.

BTW, I have gained weight since my hyst and I have seen it get worse on some HRTs than others. I gained 10 pounds in one month on one certain type - it was awful. Also I've noticed it goes to my waist immediately. That's enough to make me depressed right there!