Hi, I have been following this reaction and I have heard the reason Jo Bell got sick is because she had hugged/kissed the dogs after the promeris had been put on. It is just hearsay but this would certainly explain why she got so sick and nothing else like this has been seen. If this is what actually happened it really makes me question this reaction more and more. I have come into contact with it when putting it on my dogs and have never had any problems....and I am a very unlucky person, if something is gonna happen it always happens to me!!!