The heartworm meds we give our dogs has Ivermectin as the main ingredient. And they have had no adverse reaction to it. I think that the products you have mentioned will work just fine. The only problem I am having is, my vet doesn’t carry these brands. And you need a vet to buy the product in order for you to use it. Is there any other way I can get these products? I don’t wish to ask my vet hospital to buy them. They always inflate their products, by rather a large margin. I go to them because their vets are very good. And they take payment plans, which most other vets down here don’t do. So when ever possible I try and get the meds, and wormers from some other source. I like the idea of the Advantage multi, because it says it covers so many worms. But I would hate to use it and find that it wasn’t working. You mentioned you use Sentinel, does it help with killing flea adults? I know you mentioned it kills the eggs. Do you know of any other place I could check out the Advantage multi, for more testing that has been done on it? I know so many questions. Sorry. I just would like to make certain they are covered with the best stuff I can find. And because I do foster care, the more the med covers, the better off my dogs are going to be.