She sounds to young to have developed the "old lady" problem that I have experienced in older, spayed females, but she could be an exception. There is a hormone treatment available that saved us and my parents, on two older females, Murphy and Scout. I'll be darned if I can remember the name of it, though. Both of them developed the exact same problem in their later lives and were both spayed. It was a concotion that my vet had made to his specifications and one capsule each day (if I'm remembering correctly) took care of it for us.
I would just keep pounding your vet to try and find the right resolution to the problem. I just know there is an answer out there. And if any kind of kidney or bladder problem has been ruled out, perhaps they can get her on some hormone therapy. If you need me to check with my vet to find out exactly what it was that he was providing for Murphy and for Scout, let me know. Scout stayed with me, periodically, and their own vet didn't have the meds that Dr. Robinson (my vet) provided for her. Her problem occured while she was with me and he agreed to keep providing the medication for my parents, even though they were 3 hours from here.
Good luck to you and send me a PM if you want me to investigate further. I will be offline all next week.
Logan
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