Thank you Phred. I don't think it is a separation anxiety issue, I've been leaving her in a crate at home while I'm at work for the past month or two (besides when she was spayed and a few days here and there) and she hasn't had a problem. Usually she goes right in and doesn't make a sound (I actually video taped them one day, they spent the first bit getting the treat out of the kong then went to sleep). Though I admit she was really upset today because Nebo wasn't with her, but he was with her on Monday when she was sick.