Our Mist developed something similar on her hind paw when she was 12 years old. I noticed her favouring the back leg when she walked across lumpy ground etc... and then noticed that one of her pads seemed to have grown an axtra part similar to whats in your pictures but larger and it also looked sore like the one in your photos.
The vet said he reckoned it was caused by an old injury or something and that it had developed into a sort of growth. Antibiotics didn't sort it so she had it removed. It was awkward with the after care and keeping it dry because it was the middle of winter and always wet outside and keeping it dry was a pain. It did heal up ok though and she was an elderly dog.
I told the vet I recalled Mist getting stung on one of her back feet the previous summer when she trod on a bumble bee that was on the ground. She obviously felt it a bit at first but then she seemed ok after a few seconds and I couldn't find anything up when I looked. Whether that caused it, nobody knows for sure. but she never had a problem once it had been taken off. It wasn't that expensive to have done and it was worth it, even at her age.
I'd say get it taken off when she goes for her dental surgery.







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