Jenn,
My Io is blind and brain damaged from being thrown from a car as a kitten.
All I can tell you is it will take some time. We obviously do not move furniture around much. We also were told by our vet to use treats as a smelly safe line.
It has worked well, he has completely figured out the whole house downstairs. He is a total lap cat upstairs because the remodeling throws him off.
Now he is a bit less inclined to run up and meet new kitties, he prefers to let them come to him, and he still sometimes will bump into things but not often.

I wish you well with this boy, and if I can help with any other things about a blind wonderguy, let me know!

Kym