Quote Originally Posted by Alasse
Horses, dogs, cats etc were once non domesticated animals, meaning 'wild'

So its ok that humans domesticated these animals over hundreds of years...but humans should not attempt to domesticate any other ones...is that what you mean?

Why is it that big cats or so called 'wild' animals cannot over hundred of years be domesticated? IE Breed to coexist with humans
Well, domestic cats ARE essentially domesticated "big" cats. I think they are mostly closely related to African and European wild cats. And, it does take a lot of generations to make an entirely new species. Just like dogs are closely related to wolves, they are not wolves- they are another species. How many generations of intentional breeding this would need I have no idea.

You could never make a new species with the Liger because they are a crossbreed- and therefore sterile. If they found a way to breed a tiger/lion and the offspring was fertile this might be possible- but it would require some genetic engineering. The definition of a species is a group the can interbreed to produce fertile offspring. Lions and tigers are closely enough related that they can produce offspring, but they are not of the same species so the offspring is sterile. You cannot therefore breed a liger to a liger.