Jenn - My commiserations! I've been through this many times for over 20 years and I've never found a solution except to move the cats that are having the problems. I'm sorry to state that so baldly, but I think you have already pretty much come to the same conclusion yourself. Extra litter boxes, new litter boxes, extra attention, Feliway, isolation re-training, repeated checks for UTI, supervised trips into the garden, nothing has worked in my household on a cat that has developed this behavior, male or female.
I hate, hate, hate the fact that some of my cats have to live downstairs (my house is in a hill and I have a daylight basement with living room, bedrooms, etc.), but after having upstairs walls replaced and stripping out the carpet so I'm left with plywood subfloor with rugs thrown over it, I'm out of options. Those cats just don't get the attention the upstairs cats get and I have to make myself go downstairs and spend time with them. All their soft furniture has to be wrapped in plastic, they ruined the one sofa they had, sprayed on all the lamps and tv, so it's not a cosy place to be. Telling myself that they created this environment doesn't help the guilt or wish that things were different. I tried again last week to bring Thumper upstairs because I adore him and he longs for attention, but within hours I was cleaning spray pee off furniture and soaking my sofa in Nature's Miracle so he had to go back down. All five of them (except for Taranis) have fun downstairs together. They were all long-time shelter cats, Thumper for about 6 years, so they have a lot more freedom and comfort than they've had before, but it's far from what I want for them.
I have Taranis (female, although a male name like Boris) on Prozac and it has helped. She's never sprayed but she peed on just about anything, especially soft furniture, blankets, throws, pillows, etc. She's also now with cats that she doesn't hate quite as much as before; she will actually share the bed with them if they stay several feet away from her. She had had 4 homes in her first 3 years before I adopted her, being bounced back to the shelter for "inappropriate elimination" and not wanting to be cuddley. She should really be an only cat but that isn't going to happen. Sigh!
We share the same kind of cats - I have mostly FIV+, behavior problems and ex-ferals also, but with a couple of handicapped cats thrown into the mix.
Good luck with sorting things out, and if you come up with a good solution, please post it.





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) so don't get mad when he pee's.
(pronounced: Marley). 
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