We moved 5 cats and 1 Golden Retriever from Connecticut to Seattle - 5 day road trip with all furries in the "critter-mobile" (a Volvo stationwagon). They settled into their crates, had water and crunchies if needed, but for the most part....they slept all day and were up all night exploring the hotel room. By day two they had the routine down and we never had any potty accidents in the crates. Of course once we got to the hotel...there was a big line for the litter boxes. We usually set up 3 in the room, so there was only a short wait
We "declared" one dog and one cat at the hotel check-in, paid the fee and hauled in the rest of the crew under the radar. They were the best bunch of road warriors you could ask for and all made it to the west coast without any signs of stress or illness.
We were lucky to have such a good group of kitties and Golden.