My three cats do nicely in the car and are no trouble. I have had a couple in the past that were horrible. I got a few pills from the Vet to knock them out for a few hours....didn't put them out, just put them in a state of total relaxation. I would get at least three containers big enough to handle two cats each, with a litter -Pan. Attach a food bowl and water bowl.... Make sure there is A/C on all the time. Make sure your car radio works and turn the volume up if they get really noisey. They need lots of air, water and they need to stay in the containers. Once you get them out, they may be difficult to put back in. If your cats don't mind their containers and/or the car, then you will have no problems. I have gone as long as 10 hours at a time, keeping them contained. I would also travel at night, if you can and then the heat shouldn't be that much of an issue.
I have traveled from Burlington Vermont to Cape May New Jersey, with two cats, round trip, with not a peep out of them. Then just recently traveled from Phila. PA to Burlington with Gabe, the monster kitty, and not a peep out of him (he was given a little sedative first though).......
I would go with sedatives, litter, water, food and containers for sure!
Good luck. Keep us posted.
P. S. My cats like certain kinds of music better than others. They rather like opera - tenor stuff.
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