There's only one problem with posting that question. It is a highly charged debate, and you are probably not going to get answers that are not idealogically driven.

Groups like PETA hate all animal use, and have gone so far as to attack the March of Dimes, calling them the March of Crimes for their use of animal testing, ignoring the fact that MOD has had a significant positive impact on birth defects through its research. Animal testing of Cosmetics is IMHO ignorant, but for true medical research there are things that are hard to research any other way.