Originally posted by Kfamr
Poor you and poor Sam. I hope someone helps you out with what to do. I'm only "trained" in dog training.

{{HUGS}}
We can't forget poor kitty. There is obviously something wrong whether it be medical or otherwise. Something needs to be done to help this cat.

originally posted by Samantha Puppy
They're left alone together on days that my husband goes into the office. Otherwise he, at least, is there with them. Samantha plays with all the kitties - they like bolting out of nowhere and getting her to chase them - but I have never seen her do anything malicious towards them. She grew up with my parents OLD Maine Coon cat and because of him, "respects" cats.

I'm not saying what you suggest is impossible - I'm not discounting ANYTHING at this point. Just from the animals I know, it seems unlikely.
I am sure living with a maine coon did teach Samantha to respect cats and I don't think she would do it intentionally. But she is much bigger than they are it can take as little as a misstep by Samantha and she can step on them and hurt them. Unintentional by all mean but still the cat may see it otherwise.