readily irritates a dog's stomach. I've seen dogs given bufferin become nauseated immediately.

If you are going to give aspirin, then pre-treat with an acid blocker such as Zantac (Rantidine).

The doggy NSAIDs such as Duramaxx, or Metacam are easier on the stomach. Liver function should be monitored if the dog is on these medications for longer than a month.