If they have cages that you can pick up and put in the car I would suggest doing it that way, all separate, and driving around a bit beforehand to get them used to it. You might also have to make the trip in two days for their saftey and health. I take mine in his little travel carrierand he sits in the basket in the front od the mini van when we go to shows, and he actually doesn't seem to mind it and doesn't pee or poop if he can help it.