I can also sympathize!!! Sadie is good about leaving things alone, but Cincy is a destroyer!!! She has chewed a hole into the side of Sadie's bed, torn apart two towels we have had as cushioing in her crate, chewed the insulation off the air conditioning pipe outside, eats rope bones...you name, she'll chew it apart. we have been trying to get her out of the crate, so she has more room during the day.
Friday night, she did great. saturday morning I left her in the kitchen for less then 2 hours with sadie and she chewed a good size hole in their blanket and and started unstuffing it.

I have had moderate successs with bitter apple spray, but I hate to use it on toys...I don't want to discourage her from chewing on her stuffed animals, i just don't want her to eat them!