I have a five year old cat Spike that does this. He has the loudest gawd awful screech when he wants to. For the first few 100 times he did it I would get up and go find him see if I could see what was wrong and each and every time there was nothing remarkable. A few times he was hovering over a toy or a bug etc. I've concluded he's lonely or something or feels it's attention time.

So could be something, could be nothing. I dont think a housecat who is used to certain foods would touch something that is spoiled.

I would consult the vet if it keeps up, you never know it could be something physical or for nothing more than attention.