they should stay with the mom at least 3 weeks, but it depnds on the litter a small litter will wean faster then a large litter, for example I have raised 2 litters, 1 of 3, they were weaned in 3 weeks, the other of 6, they actually took 6 weeks to wean, having males in the litter makes it much easier to tell lol basicly when males start to rumble strut(wiggle their butt and purr) they need to be seperated NOW or they will breed back to the mom. females never have to leave their mom, all my girls live together, only males must be separated into no more then 2-3 to a cage, and 3 is a risk. any questions just ask, as I said I have raised 2 litters