To the best of my knowledge, lops are not prone to more health problems than regular rabbits.

Also, start with an ADULT rabbit, not a baby, and (IMO) a neutered male is the easiest to start with. With a baby rabbit, you never know what you are really getting(I had a very cute baby that turned into a very nasty adult rabbit), and in my experience males are mellower. Don't get me wrong, females are just as sweet, but my female rabbits were always more adventurous than cuddly.

Prepare for the fact that many rabbits don't like to be held and cuddled. A lot of them are actually quite independent. Most of my rabbits liked petting, but very few of them liked to be picked up or held.