Originally posted by smokey the elder
I use this technique:

I kneel on the ground and pin the cat between my knees. This frees up both hands. With the left I open the mouth, the right pops the pill down the hatch. I close the cat's mouth, rub the throat and blow on the nose until he swallows. Then the reward comes.
I use that method also
I got a pill plunger thingy from the vet, I find half time it's easier to use my hand.