Well, the pee issues haven't gone away completely, though they HAVE decreased. As I mentioned earlier, my pee issues are multi-faceted. It isn't JUST spraying for territorial reasons, there are aggression issues and timidness/insecurity issues (though those all have a common factor).

So, I am still doing the collars (though they seem to wear off at about three weeks in, which is when I noticed pee again), but I have added kitty prozac. Thanks to Medusa for being so patient with the explanations.

I couldn't pill them originally. I wanted two to be on it, Molly as she is the main pee'r, and the timid one that gets attacked, and Sonic, the territorial sprayer and one of the aggressors. I left Ari out of it, hoping the other two's behaviours would affect hers.

I found pill pockets for cats and cannot believe how simple that is! Two treats, two pills, I feed Molly separately, anyhow, and just put hers down on a plate, close the door, and come back five minutes later with her wet food, and she has already eaten the pill pocket. Sonic gobbles his up, and then gets his food five seconds later, as he is a very foody cat.

As for personality changes, I have noticed a calmer house. I have ten cats, and the stress of the three was resulting in fights all over, pee, tension, growling (even amongst those not directly involved). I thought I noticed some extra sleepyness with Sonic, and I still can't say it isn't true....but he is so much calmer. Sonic is what I would call an ADHD cat, he needs love and attention all the time, and he is hard to settle down. The last two days, he has seemed less anxious, not so much on 'high alert'.

Molly hasn't seemed more sleepy, but she IS more bold/brave, and I swear, that is giving off the appropriate messages to the two aggressors- Sonic and Ari. She, too, seems less on edge.

I don't know. I hate to be too hopeful, but each day is a new day....and these last few days with prozac have been nice.