Very hard to understand why you keep giving her the vac for Lyme. This would be my no.1 suspicion. I have seen many dogs react to different vacs exactly the way you describe. The rabies vac gave one of my dogs a severe case of the jitters, plus she had the weirdest bout of what we called pseudo rabies. The day after getting the shot she started being afraid of lights, shadows and her water...she would try drinking but would jump away the minute she touched the water so she was going without. Many more smaller problems and this lasted for over two weeks. Needless to say I get the puppy shots and none of my dogs get another shot for life. And none have gotten ill or contracted any communicable disease.