Jen, my Puddy has been on subQ's for a couple of years now and it's made quite a difference in how she feels and acts. As others have mentioned, my vet recommended using a larger gauge needle in order for the treatments to go faster and, although it is a little more uncomfortable upon insertion, the treatment goes so fast that I feel it's worth it. Puddy has always been a very impatient and aggressive cat and to have a treatment take longer than it has to just isn't worth it to either of us. I also move the needle to a different spot each time so that the area doesn't become sore. It's also important to use a new needle each time or at least every other time so that it's more comfortable. Puddy gets 150 cc's and I use my judgment as to how often. In the beginning, she was getting 2 treatments a day, then I backed off to 1 a day for a while, then 1 every other day, then every two days, etc. If she looks scruffy ie. somewhat dehydrated, she gets a treatment.

As for vomiting, my vet said that if she throws up once, not to worry but if she throws up twice in one day, to call him, especially if it's bile and not food. Believe it or not, Puddy actually likes canned KD now, which is especially for cats in renal failure and it also comes in dry form but she isn't too hot on that. I also sprinkle Forti Flora on her food; it's a pro-biotic that's quite palatable and it helps her w/bowel movements. It's great for cats who get diarrhea often or who, like Puddy, tend to have mushy stools.

Trust your judgment as to how often to give the subQ's unless your vet told you specifically how often to give them. Puddy always perks up after one. You can't hurt Braveheart by giving him too much. He may get a little pocket of fluid, though. Puddy gets an accumulation right under her front right leg but, after a while, it goes down. It doesn't harm them in any way. And when you first administer the subQ, Braveheart may squeal a little and that's because it feels funny when it first goes in.

Braveheart will get used to his treatments and so will you. It'll become so easy that you won't think anything of it after a short while.