Yes, Clomicalm is by prescription. My vet had some in stock and gave me enough for both Specs and Yodie. Check out this website:
http://www.ah.novartis.com/products/...clomicalm.shtm

As I mentioned earlier in another thread, it was originally prescribed for dogs w/separation anxiety but has been successfully used w/cats. Of course, talk to your vet about its use as you would w/any medication. But I tried Buspar to no avail and amitryptilene which worked for a little while but it had side effects. So far, Clomicalm is the one I like and the cats don't even put up a fuss any more when I pill them because they get 1/4 pill (5 mg.) and it goes down easily. Good luck w/whatever you decide.

Blessings,
Mary