I wouldn't suggest leaving your door open with just a baby gate up unsupervised. They can esily jump those. Bitter apple is good but it dosen't always work most bunies usually just like it. And I also foudn that it stay on your own hands after spraying it and man oh man that stuff taste AWFUL!!! I don't really know what you ment by she wouldn't settle down though because I would think if she's just running in your room she wouldn't make thta much noise. As for the holding thing. She is a bunny they are prey animals and don't like being chased or picked up because they translate it as your going to eat them. If you want her to let you pick her up sit on the floor and let her come to you and bribe her with treats etc. Good luck let us know what happens tonight.