What a bad situation. I do suggest you try valium or something like that for her. We use it on Ripley now and then to help him chill out which in turns curbs his urge to spray. His is all stress and behavioral so if stress is her issue then medicating her would probably help at least some. Definitely worth trying and with Valium I see a quick affect. It doesn't take long to work on him. I do hate to see him drugged but honestly it's better than him being stressed, pulling out his fur and peeing inappropriately. He's just one laid back happy guy.