Ditto to everything above.

When my husband and I brought our two cats to Louisiana from Oregon, it was a long drive. We drove through California, Arizona, New Mexico, and Texas. It took about four or five days as we had to stop for various things. Isis cried until we figured out (about 3/4s of the way) to switch crates and she was fine.

We lined their crates and gave them food and water BUT they refused to use it until we stopped for the night.