Cats are usually good at hiding pain, but with her turning on your spouse and you, it sounds like she is really uncomfortable.
Good luck at the vet's. It could be a blockage or something similar.
I hope you and your vet can find a nutritious food that she likes - often, when a cat likes to eat strange things, something is missing in their diet.
Prayers going out to your sweetheart kitty.
"I have six locks on my door all in a row. When I go out, I lock every other one. I figure no matter how long somebody stands there picking the locks, they are always locking three." -- Elayne Boosler