Cats are usually good at hiding pain, but with her turning on your spouse and you, it sounds like she is really uncomfortable.
Good luck at the vet's. It could be a blockage or something similar.
I hope you and your vet can find a nutritious food that she likes - often, when a cat likes to eat strange things, something is missing in their diet.
Prayers going out to your sweetheart kitty.
"When I think of Mick Jagger still singing that he can't get any satisfaction in over forty years of being in the Rolling Stones, I have to conclude that he's either lying or not all that bright." -- Henry Rollins